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Secreted in our bodies by the liver, glutathione is also available in plants (which is where we get it)

NAC Administration Ameliorates TNBS plus Ethanol Induced Mucosal Injury To test whether the early TNBS+ethanol-induced GSH depletion was important for the development of colitis by rendering mucosa susceptible to the TNBS+ethanol-induced ROS overgeneration, we examined the effect of NAC, a GSH precursor, on both mucosal GSH content and extent of injury in TNBS+ethanol-treated rats

The confidence is remarkable given the near-total absence of clinical evidence behind most of it

Some prescription drops can cause gradual darkening of eye color, but they are intended for treating eye conditionsnot cosmetic useand the change is usually subtle and irreversible