The results are inconclusive, but there are some promising results so far: In one small study with just 12 (healthy middle-aged non-smoker) subjects (taking either 500 or 1,000 mg per day liposomal glutathione for four weeks), there was a trend for increasing glutathione levels, although it only became significant in the 500 mg dose after two weeks, which was also the largest increase at 25%
Glossary Organotypic cultures Cell culture systems prepared from slices of neonatal or early postnatal brain, in which the general synaptic and circuit architecture is preserved
Many people, particularly those in northern climates or with limited sun exposure, require dietary sources or supplementation to maintain adequate vitamin D status year-round
In terms of sustained antidepressant efficacy and downstream long-lasting synaptic plasticity, there is also a body of important evidence for the ketamine metabolite (2R,6R)-hydroxynorephedrine (2R,6R-HNK)