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Because the pathophysiology of obesity is complex, single-targeting agents have limited efficacy, suggesting that drug therapies that target multiple mechanisms are more effective than single-targeting agents (10)

Cellular metabolic dysfunctions may represent the biological substrate connecting depression with different cardiometabolic outcomes and a key pathway in depression pathophysiology potentially accessible through AC metabolism

Obesity, insulin resistance, diabetes and cardiovascular risk in children: an American Heart Association scientific statement from the Atherosclerosis, Hypertension and Obesity in the Young Committee (Council on Cardiovascular Disease in the Young) and the Diabetes Committee (Council on Nutrition, Physical Activity and Metabolism)

FDA Warning Letters: Beyond pharmacies, the FDA has also issued warning letters to website retailers selling BPC-157