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Elements such as miRNAs (e.g., miR-92a) and long non-coding RNAs (lncRNAs) can either enhance or suppress NO production in response to physiological conditions (Lin et al., 2005

Supportive care further enhances management by focusing on symptom relief and improving quality of life

Additionally, correcting hypo-functioning thyroid, treating iron and zinc deficiency (and other documented macro and micronutrient deficiencies) also help ameliorate symptoms (94, 95)