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It acts as a potent agonist of the IGF-1 receptor, activating signaling pathways such as PI3K/Akt and MAPK to promote: Cell Growth and Division : Enhances proliferation in diverse cell lineages, including ectodermal (e.g., oligodendrocytes, motor neurons) and mesodermal (e.g., osteocytes, chondrocytes, muscle cells) types, supporting stem cell research and large-scale biopharmaceutical manufacturing

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Some researchers use both, with topical for local effect and injection for systemic support