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Rotating sites each week reduces irritation

Even though you're usually supposed to take a dose every seven days, there's a window for flexibility because the medication builds up a steady state over time in the body

Tirzepatide and GIP treatment lead to significantly lower interleukin-1 beta (IL1B) levels and Tirzepatide further lowered interleukin-6 (IL-6) and monocyte-chemoattractant protein-1 (MCP-1) levels, highlighting distinct tissue-specific regulatory roles in pancreatic adipose tissue metabolism and inflammation [32]

If you have to be on a medication, work with your medical provider to take the drug in the smallest dose possible for the least amount of time