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Hofstetter CP, Schwarz EJ, Hess D, Widenfalk J, El Manira A, Prockop DJ, et al

Good hygiene can help prevent this

2003 May-Jun;57(3-4):145-55

Lastly, SGLT2i can indirectly influence WAT metabolism by increasing the expression of myocardial FGF-21, which promotes angiogenesis and upregulates genes associated with brown adipocyte characteristics, such as UCP1, PGC-1, and PRDM16, shifting white adipose tissue from energy storage to energy dissipation thus confirming the positive metabolic effect of this class of drugs