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Despite best efforts, it is possible that some patients will not comply with fasting recommendations while continuing their GLP-1 RA

First, they need to be well-detailed mechanistic studies that disentangle causal relationships between specific microbes and neurological outcomes rather than mere correlational evidence that would lead to therapeutic targets

The GlyNAC combination (glycine + NAC) showed multi-system improvements in a 16-week RCT in older adults, including corrected glutathione deficiency, reduced oxidative stress, improved mitochondrial function, and enhanced physical performance