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The biological rationale is strong: GLP-1 receptor signaling is dose-responsive, and even partial activation appears to influence insulin sensitivity and inflammatory pathways
Pregnant individuals should not use tirzepatide due to insufficient safety data in pregnancy
Longer telomeres = slower aging and reduced risk of age-related diseases
It appears that the journal has decided that these concerns warrant retraction, and we respect the publications process for making decisions in these matters. In the last few years, Lee has retracted two other papers and issued multiple editorial statements, according to Retraction Watch
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