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The GLP-1 onset timeline rewards patience, which is the opposite of what most people expect from a weight loss medication

The research is unambiguous on this point (Mozaffarian et al.)

Who Mounjaro Is Best For Mounjaro tends to be especially effective for individuals who: Have type 2 diabetes or significant insulin resistance Experience strong cravings for sugars or refined carbohydrates Struggle with portion control despite sincere efforts Have metabolic syndrome or elevated A1C levels Prefer a once-weekly medication with powerful metabolic effects Have not achieved adequate results with GLP-1-only therapies Need a strong appetite and craving regulator to support long-term goals Mounjaro may also be used in the preoperative phase for bariatric surgery candidates with diabetes, helping reduce surgical risk and stabilize blood glucose before the procedure

Best Pract Res Clin Obstet Gynaecol (2011) 25(3):28799