A Phase III award can be issued on a sole-source basis, meaning no further competition is required
For example, certain intestinal bacteria, such as Bifidobacterium , Clostridium , Enterococcus , Lactobacillus , and Pediococcus , can convert amino acids into polyamines through decarboxylation (111)
At higher concentrations, the relative loss is smaller, but it still occurs
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