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MKRN3 circulating levels in Prader-Willi syndrome: a pilot study

These changes were accompanied by a decrease in numerous myocardial proteins related to lipid homeostasis and cardiac fibrosis ( Figure S9 ), providing a protein-level basis for the histological and functional improvements observed

Only in the presence of clinical signs suggesting an underlying disorder (malabsorption, chronic losses, or inadequate nutrition) should additional studies be considered.3,6 Physiological nail findings