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*Correspondence: Mirjana T

In mild cases, simple lifestyle changes and home remedies may be enough to manage symptoms by: Properly resting the affected hand and wrist for at least two weeks Applying cold packs to reduce swelling Wearing a wrist splint at night to keep the wrist straight Performing gentle stretching exercises for the hands and wrists Taking nonsteroidal anti-inflammatory drugs (NSAIDs) for pain relief For more severe cases or if symptoms persist, your doctor may recommend: Corticosteroid injections to reduce inflammation and relieve pressure on the median nerve Physical therapy to strengthen and stretch the wrist and hand muscles Surgery to release the ligament pressing on the median nerve

All work is non-clinical and mechanistic in nature

Androgens/AR signaling affects mitochondrial morphology