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[16] [19] Some research suggests these anti-inflammatory effects may occur alongside weight loss, though the relative contributions of direct immunomodulation versus metabolic improvement remain unclear

Villanueva-Millan MJ, et al

When to Talk to Your Healthcare Provider If you have diabetes or are taking semaglutide for weight management, its important to have an open line of communication with your healthcare provider

Moreover, a significant fraction of subjects, commonly referred to as treatment-resistant, do not respond to these antidepressants despite the use of various therapeutic strategies (173)