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There are no major safety concerns with either peptide in diabetes patients, but Semaglutide has more clinical experience

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Biological Functions Beyond Glucose Metabolism: DPP-4 is a protein that not only digests other proteins, but also plays a crucial role in important body processes, such as how cells grow, move, and connect with their environment, known as the extracellular matrix [5]

The Obesity Medicine Association recommends 150-300 minutes of moderate aerobic activity or 75-150 minutes of vigorous exercise weekly, plus resistance training twice per week, for sustainable weight management and overall wellness