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Overall, these studies suggest that the related genes and genetic loci has increased our comprehension of the immune-mediated pathways involved in its pathogenesis and natural history

This ROS-driven cascade converges on microvascular dysfunctioncharacterized by dysregulated vasodilation, compromised endothelial barrier function, and increased vascular fragilityultimately manifesting as mucosal erosions and hemorrhage, the hallmark features of PHG [373]

Transport it in a small cooler with a cold pack to maintain a refrigerated temperature

Statistical analysis All experiments were performed in triplicate, and the data were expressed as means standard deviation