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It is a recognized risk factor for conversion from minimally invasive to open surgery [57], which increases wound complications and may delay adjuvant therapy

The authors concluded that GLP-1 receptor agonists are a safe and effective adjunct treatment for weight reduction in women with PCOS. A 2025 review of human and animal studies concluded that GLP-1 receptor agonists offer a multifaceted approach to PCOS management, with benefits across both metabolic and reproductive domains, including improvements in insulin sensitivity, weight loss, and menstrual regularity, with emerging evidence suggesting possible effects on gut microbiota composition

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