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In pediatrics, most available studies do not stratify outcomes by sex, underscoring an important knowledge gap and the urgent need for research that addresses sex-specific responses during childhood and adolescence

Hypotension leads to renal hypoperfusion and I/R injury, and intestinal congestion promotes endotoxin production, which would result in AKI (Yuan et al., 2019)

48 , 50 , 48 In 1 of the studies that assessed the psychometric properties of the IWQOL-Lite questionnaire, a community-based sample of 492 individuals who are living with overweight or obesity (mean BMI 27.4 kg/m 2 ) who were not undergoing weight-loss treatment completed the IWQOL-Lite

Regarding thyroid function, immunological modulation, and redox equilibrium, its essential to keep Se consumption within the physiological range, as both low and high levels might lead to adverse clinical effects [17]