retatrutide fda approval status 2024 produces up to 30.3% weight loss in Phase 3 trial Retatrutide just took a major

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While most people tolerate them well, its helpful to know what side effects to expect, especially in the first few weeks of treatment: nausea vomiting diarrhea constipation headaches fatigue These symptoms are well-documented across clinical trials and often appear during the dose escalation phase

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J Biol Chem 259(3):183441 Xie S, Zhang M, Shi W, Xing Y, Huang Y, Fang WX, Liu SQ, Chen MY, Zhang T, Chen S, Zeng X, Wang S, Deng W, Tang Q (2022) Long-term activation of glucagon-like peptide-1 receptor by dulaglutide prevents diabetic heart failure and metabolic remodeling in type 2 diabetes