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The convenience of consistent abdominal injection often outweighs theoretical benefits of local injection for this reason

Neurofibrillary tangles but not senile plaques parallel duration and severity of alzheimer's disease

An imbalance between ROS production and the antioxidant defence systems results in oxidative stress that can cause cellular damage, inflammation, and impaired physiological functions [83]

In addition, the ROS produced by ATMs first affect their recruitment and polarization, especially in cases such as diabetes, ROS induces ATMs to polarize towards M1 and the release of inflammatory factors (145, 146)