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Moreover, significant changes in the activities and gene expression of key enzymes, including catalases, peroxidases, and superoxide dismutases, highlight the critical role of antioxidant mechanisms in plant responses to stress

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A 2025 paper published in BioImpacts confirmed topical GHK is increasingly being studied as a clinical anti-aging compound with hair restoration applications and that injectable forms are now entering clinical interest following the FDA's April 2026 decision to remove GHK-Cu from the Category 2 restricted list

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