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J Craniomaxillofac Surg

Applying products with high-strength vitamin C (L-ascorbic acid) or directly combining them with acids (like almost any AHAs/BHAs) is counterproductive, says Shamban, because the low pH of these acids can degrade the peptides, reducing their efficacy

Indeed, adipose tissue inflammation was shown in various animal models of adipose tissue-specific reduction of proinflammatory potential to be required as an adaptive response, allowing proper storage of excess fat and filtering of gut-derived endotoxins [80]

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