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A large 2025 study published in Blood Advances examined more than 540,000 patients with type 2 diabetes across 21 countries and found that those taking GLP-1 medications had about a 20 percent lower risk of venous blood clots compared to those taking a different class of diabetes drug

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Self-pay will continue to lead access in many countries, driving new routes to patients through direct-to-patient models, employer programmes and digital health platforms