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Our findings concerning Semas modulation of NR4a1 through the Creb5 pathway offer insights into potential treatments for cardiovascular diseases, paving the way for future research in this domain

GLP-1 drugs (glucagon-like peptide-1 receptor agonists) are medications developed to treat both type 2 diabetes and obesity by correcting hormonal imbalance - stimulating insulin release and suppressing excess glucagon -to bring blood sugar back under control

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The dual weight-reducing mechanisms can facilitate clinically significant weight loss whilst improving glycaemic control