retatrutide triple hormone receptor agonist benefits Medscape | The investigational GLP-1/GIP/glucagon produced significant weight loss and A1c reduction in people Use of an unapproved triple-hormone

They may recommend prescription options like lubiprostone (Amitiza), linaclotide (Linzess), or prucalopride (Motegrity), which work through mechanisms different from over-the-counter options and can be combined with the lifestyle strategies outlined here

3 Obesity currently affects over one billion individuals worldwide and, in 2024, was directly implicated in over 3.7 million deaths

However, many patients have experienced severe and sometimes life-threatening side effects, including gastroparesis, pancreatitis, and vision problems

Glucagon-like peptide 1 receptor agonists and 13 obesity-associated cancers in patients with type 2 diabetes. JAMA Network Open