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Gastroenterology (2007) 132(6):213157

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108 Elevated concentrations of these inflammatory cytokines have been detected in the plasma and cerebrospinal fluid of patients with AD, 109 and postmortem analyses revealed an inflammatory milieu within the AD brain, 110 implicating inflammation as a contributory factor in the pathogenesis of dementia

Over the following weeks most people notice improved energy and less brain fog first, with skin looking less dull (weeks 12), then steadier energy, brighter and more even skin, and faster recovery (weeks 24), then noticeably clearer skin, stronger immune response, and better stress tolerance (weeks 412)