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Epitalon, also known as epithalamin or epithalon, is a synthetic tetrapeptide composed of Ala-Glu-Asp-Gly, derived from a naturally occurring pineal gland extract called epithalamin

Receptor Subtype Selectivity Although MC4 receptors are strongly associated with appetite regulation, Melanotan II also activates MC3 receptors with overlapping pharmacologic activity

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Although the expression of extrapituitary prolactin in adipose tissue and immune cells has been reported, its quantitative contribution to circulating prolactin levels and functional significance in human metabolic regulation remain unclear