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Neuropharmacology 200:108807 Marty VN, Farokhnia M, Munier JJ et al (2020) Long-acting glucagon-like peptide-1 receptor agonists suppress voluntary alcohol intake in male Wistar rats

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Similarly, when we are exposed to extreme free radical insults such as from ingesting or breathing in toxins or undertaking extreme exercise we rapidly deplete our cells of its glutathione reserves resulting in injury generating oxidative stress