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Typical findings may include: Low hemoglobin Low hematocrit Elevated mean corpuscular volume (MCV) Enlarged red blood cells General laboratory ranges often include: Serum folate below 2 ng/mL may indicate deficiency Serum vitamin B12 below 200 pg/mL may indicate deficiency Additional testing may be recommended when results fall into borderline ranges

PRDM16 expression exhibited a strong correlation with gut microbiota in subcutaneous adipose tissue obtained from morbidly obese patients post-gastric bypass surgery, indicating that gut bacteria may influence PRDM16-mediated regulation of human energy metabolism and insulin sensitivity 81

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