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Instead, it has been a dysfunctional mess, a tangled web spun by all major players in the U.S

Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA Email: [email protected] ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 1 College of Medicine, University of Florida, Gainesville, FL 32608, USA ORCID: Affiliation: 2 Department of Neurosurgery, University of Florida, Gainesville, FL 32608, USA ORCID: Explor Drug Sci

Smaller, more frequent meals (4-5 per day rather than 2-3) tend to be better tolerated with retatrutide than with tirzepatide, where 3 moderate meals often work fine

If 8mg produces good weight loss results with acceptable tolerability, remaining at that dose is a clinically reasonable outcome