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Given the promising results in pre-clinical models (even in the absence of T2D), a unique mechanism of action and multiple age-related reduced disease risks that have been reported with acarbose, support for clinical trials with acarbose focusing on aging-related outcomes and incorporating biological sex, age at treatment initiation, and T2D-dependence within the design is warranted
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This is a double-blinded, randomized controlled trial that evaluated the change in HbA1c at 26 weeks with placebo compared with oral semaglutide at doses of 3 mg, 7 mg and 14 mg (1:1:1:1) in 703 adult patients with untreated type 2 diabetes mellitus (T2DM)
A: A typical procedure will take around an hour, including local anesthesia and the procedure itself
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