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Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy

This hypothesis was confirmed by several studies that had reported an important correlation between GSH levels and its positive effect on the active vitamin D ratio in the body where they showed that GSH deficiency is associated with increased oxidative stress where they epigenetically alter vitamin D regulatory genes and, as a result, the suppressed gene expression decreases vitamin D biosynthesis, ultimately leading to a secondary deficiency of vitamin D3

The use of in vitro 3D cell models in drug development for respiratory diseases, in Drug Discovery and development

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