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Inadequate fiber intake in children on KDT is poorly understood and could go beyond constipation and gastrointestinal discomfort 29

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For instance, the yield of the RCM product would be low if the side-chain orientation of the alkene pair is not in close proximity, and the separation of Grubbs catalyst from the product by high-performance liquid chromatography (HPLC) is difficult, it is also challenging to control E/Z isomerism and distinguish between the isomers by solution nuclear magnetic resonance (NMR) spectroscopy [91, 92]