Wanner C, Lachin JM, Inzucchi SE, Fitchett D, Mattheus M, George J, et al
Not sure which kind of discoloration you have
The results on DJ-1 are, therefore, inconsistent and should not be considered as a marker of PD
For oral contraceptive pills: Take your pill at a time of day when nausea is minimal (usually not within 2 hours of your Zepbound injection) If you vomit within 2 hours of taking the pill, treat it as a missed dose (follow package instructions for missed pills) If GI side effects are persistent, consider switching to a non-oral method (patch, ring, IUD, implant, injection) For non-oral contraceptives (patch, ring, IUD, implant, injection): No interaction concern These methods don't rely on GI absorption For barrier methods: No interaction The FDA label for Zepbound states: "Tirzepatide causes a delay in gastric emptying and may impact the absorption of concomitantly administered oral medications." This is a general statement about all oral medications, not specific to contraceptives