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Balloon valvuloplasty may be done to relieve the valvular obstruction in moderate or severe cases

The exact underlying mechanisms arent fully settled (and we need future studies), but there are a few strong theories at a cellular level that line up with what we see clinically

Rapid blood sugar changes : Semaglutide's rapid lowering of blood sugar may disrupt blood flow to the optic nerve, potentially triggering NAION in susceptible patients, per a case report published in Clinical Practice and Surgical Cases