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Research has documented GSH depletion as a risk factor for chronic inflammatory and respiratory conditions, including chronic obstructive pulmonary disease (COPD) and atherosclerosis

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In this, calvariectomy and/or laparotomy (used to assess intracranial (superior sagittal sinus), portal, inferior caval vein and aortal pressure, and brain swelling and organs lesions and vessels presentation) since used in the therapy to counteract increased intracranial pressure and abdominal compartment syndrome [56,57], did not further contribute to the worst circumstances created by the occlusion of the superior sagittal sinus

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