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This work also was supported by Guangdong Province-Provincial Chinese Medicine construction special fund named Traditional Chinese Medicine Inheritance Studio construction project Guangdong Chinese Medicine Office Letter (2023) 108

Under physiological conditions, proactive proteostasis mechanisms establish and preserve baseline proteome quality

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These subcellular alterations not only directly damage structural cells (e.g., airway epithelium) but also release damage-associated molecular patterns (DAMPs) and oxidized lipids that activate and recruit immune cells (85)