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"I think the nail in the coffin, as they say, was when they completely made a new drug the pill a compounded version of it and basically tried to introduce that to the market," he said

10.3389/fendo.2019.00704 34 KahalH.KilpatrickE.RigbyA.CoadyA.AtkinS

Shan Y, Tan S, Lin Y, Liao S, Zhang B, Chen X, Wang J, Deng Z, Zeng Q, Zhang L, Wang Y, Hu X, Qiu W, Peng L, Lu Z (2019) The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke

Based on this result, the authors argue that antagonism of the ghrelin system may exacerbate rather than ameliorate obesity