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This paper reviews the regulatory effects of metformin on the gut microbiota, such as increasing the abundance of genus Akkermansia , enriching short-chain fatty acids (SCFAs)-producing bacterial genus, and regulating gene expression of certain genera

Evidence specific to athletic or bodybuilding use in healthy young adults remains limited and largely anecdotal rather than drawn from controlled human trials

Biochemistry 41:22542263 Bae S, Oh K, Kim H, Kim Y, Kim HR, Hwang YI, Lee DS, Kang JS, Lee WJ (2013) The effect of alloferon on the enhancement of NK cell cytotoxicity against cancer via the up-regulation of perforin/granzyme B secretion