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Here, we have utilized liver-specific overexpression of cation transport regulator homolog 1 (Chac1), a recently identified intracellular GSH-degrading enzyme, to induce hepatic GSH depletion during MASLD progression

In adults with PraderWilli syndrome, elevated ghrelin levels are more consistent with hyperphagia than high PYY and GLP-1 levels

To address inequities in dementia care, the GUIDE model offers a variety of financial and technical supports to ensure participating safetynet organizations can develop their infrastructure, improve their care delivery capabilities, and participate successfully to reach all patients, especially dually eligible populations (populations eligible for both Medicare and Medicaid) and those in underserved areas such as rural communities