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They are more useful in research protocols.39 12 In the differential diagnosis of the patient with cirrhosis and HE, laboratory (serum electrolytes, infection markers, kidney function, liver function, acid-base balance, peritoneal fluid, and cerebrospinal fluid), imaging (brain tomography or magnetic resonance imaging), and microbiologic (cultures) studies are recommended

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HED (mg/kg) = Rat (200 mg/kg) (6/37), HED (mg/kg) = 200 0.162 = 32.43 mg/kg, HED for 70 kg patient = 32.43 70 = 2.27 g