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However, there are only a few trial studies being done in this regard, and they are still approved to be used only as injections or pills and not skin patches

Delayed gastric emptying may reduce the effectiveness of oral hormonal contraceptives

Some practitioners theorize that establishing robust GLP-1-supporting gut bacteria before discontinuing medication could provide a partial buffer against rebound effects, maintaining some degree of natural GLP-1 production even after the pharmaceutical support is removed