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Common mental health disorders included a history of mental health issues (49.4%), mood disorders (22.9%), substance use disorders (14.4%), anxiety (9.6%), and schizophrenia (2.4%), with a slight male preponderance (44)

It is expected that tirzepatide will occupy a greater percentage of GIPR than GLP1R (4.1, 4.6, and 6.3 fold, respectively, at 15, 10, and 5 mg) [16]

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