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Safety: Minimizes risk of overdose or underdose

With tesamorelin, the most likely adverse events, according to the clinicians we know, are mild flu-like symptoms such as fatigue, headache, and nausea, but its also associated with an increased risk of cancer owing to its activity on growth hormone5 certainly more worrisome than the gastrointestinal problems linked to GLP-1 RAs

That said, some GLP-1 injectables are once a week, which some may find more convenient than having to remember to take a pill each day

In a study by Ishibashi et al., GLP-1 was shown to dose-dependently inhibit gene expression for advanced glycation end products receptor (RAGE) in HUVEC via activation of cyclic AMP pathways and decrease reactive oxygen species generation [103]