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Macrophage Nrf2 activates genes encoding CD36, heme oxygenase-1 and other stress proteins in response to oxLDLs and other byproducts of lipid peroxidation (240)

Any impulses fired from elsewhere in the heart before or concurrently with SA node firing can lead to premature heartbeats or sustained abnormal heartbeats

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The extent of the increase, which seems to be genotype dependent, was about 2-fold at 9 C after 4 months or up to 1.8-fold at 4 C after 7 months 151,152