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Lowered Risk of Major Adverse Cardiovascular Events: In patients with type 2 diabetes and high cardiovascular risk, tirzepatide has been associated with a lower risk of major adverse events like heart attack or stroke compared to other treatments

In a study (New-Onset Nonarteritic Anterior Ischemic Optic Neuropathy and Initiators of Semaglutide in US Veterans With Type 2 Diabetes) published on February 12, 2026, participants who started taking semaglutide were about 2 times more likely to develop NAION than participants who took sodium-glucose cotransporter-2 inhibitors

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