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@HernandezLipidsOxidativeStress2016 At high blood ethanol levels, the microsomal ethanol-oxidizing system (CYP2E1 isoform, located in the smooth endoplasmic reticulum) also has an important role

Selenite incubated with NADPH and mammalian thioredoxin reductase yields selenide, which inhibits lipoxygenase and changes the electron spin resonance spectrum of the active site iron

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This selective activity enables researchers to study lipid degradation and fat-store management without extensive hormonal effects