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The US Food and Drug Administration (FDA) has determined the shortage of glucagon-like peptide 1 (GLP-1) medication, semaglutide, is resolved

The GLP-1 receptor agonists work by mimicking the GLP-1 hormone in the gut, and the dual agonists work by mimicking both the GLP-1 and GIP hormones, which regulate blood glucose and appetite

For patients losing significant weight on compounded semaglutide or tirzepatide, topical GHK-Cu is sometimes used to support skin elasticity, though specific evidence in this population is limited

Each participant was followed up from initiation of treatment to the first occurrence of any of the measures, follow-up loss, death, or for a year after initiation of treatment