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The skin on our limbs is thicker, meaning a tan can settle deeper and look duller than it does on the face

doi: 10.1016/j.jpeds.2016.10.019 23

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Activation of Notch signaling and the expression of its downstream target gene, hairy and enhancer of split 1 ( Hes1 ) in TA cells repress the expression of transcription factors crucial for entry into the secretory lineage including atonal homolog 1 ( Atoh1 ) and induce absorptive cell fate commitment