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In some embodiments, administration of formulation or composition or device described herein reduces damage to cochlear structures caused by underlying conditions (e.g., bacterial meningitis, autoimmune ear disease (AIED)) allowing for successful cochlear device implantation

High levels of histamine : While histamine per se does not directly lead to more estrogen production, high estrogen encourages mast cells to produce higher levels of histamine while suppressing the DAO enzyme responsible for breaking down histamine, especially when there is low progesterone

Animal studies have shown that topical copper peptides can significantly increase hair regrowth compared to controls.-Cu and hair growth are still limited, preclinical and anecdotal evidence is strong

Overall, more high-quality research is needed to define the doses and clinical effects of this fascinating herb